The Significance of Nigella sativa on Histomorphological Variations of Seminiferous Tubules in Doxorubicin Treated Albino Rats

Objective: To analyze the impact of nigella sativa on Histomorphological changes in doxorubicin treated albino rats.
 Research Design: Experimental research.
 Abode Study: Anatomy Department, BMSI, Karachi, Pakistan.
 Materials and Methods: Piloted 40 rats for 35 days Department BMSI. They were 3-4 months old about 221 to 238 gm weight. Rats separated into 4 groups, Ao, Bo, Co & Do. Ao represented as control, Bo recieved Doxorubicin (DOX) 0.003g/1000g/ at 7TH day intraperitonealy, Nigella 1000mg/1000g everyday oral along with intraperitonealy Do 1000mg/kg oral. At end experiment, dissected conserved slides staining.
 Results: showed loss normal architecture seminiferous tubules diverse level atrophy while condition was improved which given extract sativa.
 Conclusion: Our result tells us that amended histomorphological changes.